Methyl 2-ethyl-3-oxopentanoate → HCID 135890158, compound

HRID 539880Notes

Reaction equation

HRID 539880 reaction equation
[O:1]1[CH:5]=[N:4][N:3]=[C:2]1[C:6]1[CH:7]=[CH:8][C:9]([O:15][CH2:16][CH2:17][CH3:18])=[C:10]([CH:14]=1)[C:11]([NH2:13])=[NH:12].[CH2:19]([CH:21]([C:26](=O)[CH2:27][CH3:28])[C:22](OC)=[O:23])[CH3:20]>>[O:1]1[CH:5]=[N:4][N:3]=[C:2]1[C:6]1[CH:7]=[CH:8][C:9]([O:15][CH2:16][CH2:17][CH3:18])=[C:10]([C:11]2[NH:13][C:22](=[O:23])[C:21]([CH2:19][CH3:20])=[C:26]([CH2:27][CH3:28])[N:12]=2)[CH:14]=1

Participants

3

Reactant 2

HCID 11643972Methyl 2-ethyl-3-oxopentanoateHCID 67455237HCID 67455237, compound

Product 1

HCID 135890158HCID 135890158, compound

Procedure

The title compound was prepared by reacting the compound of example 8 with methyl 2-ethyl-3-oxovalerate in the same manner as that of example 1. 1H NMR (CDCl3) δ: 8.69 (1H, d), 8.51 (1H, dd), 7.05 (1H, d), 4.14 (2H, t), 2.69 (4H, m), 1.92 (2H, m), 1.31 (3H, t), 1.21 (3H, t), 1.12 (3H, t).

Sources & evidence

ORD record
ord-eb92a63418ed47cd99317505a7c81c07
Source dataset
uspto-grants-2014_10
Patent number
US08871777B2

Reaction notes

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