HCID 66697404, compound → HCID 66697493, compound

Participants

Reaction Steps

A mixture of the bromo compound from Example 126 (150 mg, 0.2 mmol), CuCN (50 mg, 0.6 mmol) and DMF (3 mL) was refluxed under N2 protection overnight. The mixture was purified by RPLC to afford the product. MS (ESI) m/e (M+H+): 679. 1H NMR (CDCl3) δ: 7.73-7.70 (m, 4H), 7.38-7.29 (m, 4H), 7.21-7.04 (m, 6H), 4.63-4.60 (m, 1H), 4.49-4.47 (m, 1H), 3.81-3.59 (m, 4H), 2.48-1.97 (m, 8H).

Provenance & Evidence