HCID 71254646, compound → HCID 86691372, compound

HRID 539972Notes

Reaction equation

HRID 539972 reaction equation
[N:1]([CH2:4][C:5]1([CH2:11][N:12]=[N+]=[N-])[CH2:8][S:7](=[O:10])(=[O:9])[CH2:6]1)=[N+]=[N-]>CO.[Pd]>[O:9]=[S:7]1(=[O:10])[CH2:8][C:5]([CH2:11][NH2:12])([CH2:4][NH2:1])[CH2:6]1

Participants

4

Reactant 1

HCID 71254646HCID 71254646, compound

Product 1

HCID 86691372HCID 86691372, compoundYield 94.7%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A solution of 3,3-bis-azidomethyl-thietane 1,1-dioxide (1.0 g, 4.63 mmol) in methanol (10 mL) was stirred in the presence of 10% palladium on carbon (0.2 g) under hydrogen atmosphere overnight. The resulting reaction mixture was filtered and the filtrate was concentrated in vacuo to afford 720 mg of the desired product.

Workup

  1. customThe resulting reaction mixture
  2. filtrationwas filtered
  3. concentrationthe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-abb606a54ac149beb2ad09e165d0c5ca
Source dataset
uspto-grants-2014_10
Patent number
US08871756B2

Reaction notes

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