反应详情

A solution of 2,4-dichloro-6-methylquinazoline (645 mg, 3 mmol) and 3-(aminomethyl)oxetan-3-amine (340 mg, 3.3 mmol) in methanol (15 mL) was stirred at room temperature overnight. After the resulting mixture was concentrated in vacuo, the residue was purified by column chromatography (eluting with 10% methanol in dichloromethane) to afford the desired product.

1. concentrationAfter the resulting mixture was concentrated in vacuo
2. customthe residue was purified by column chromatography (eluting with 10% methanol in dichloromethane)