HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 178525610, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-butyl 3-hydroxy-3-(1-trityl-1H-imidazol-4-yl)propanoate | HCID 12150308 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178525610 | HCID 178525610 | — |
Reaction Steps
3 ml of trifluoroacetic acid are added to a solution of 1.4 g (3 mmol) of tert-butyl 3-hydroxy-3-(1-trityl-1H-imidazol-4-yl)propanoate in 7 ml of dichloromethane. After stirring for 4 hours at ambient temperature, the reaction medium is concentrated. 0.5 g of crude product is used directly in the next stage.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871187B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-502f1f63e082417dae53fc084bc1e4e3 |
| Source note | uspto-grants-2014_10 |