HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrobenzaldehyde → HCID 67126855, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrobenzaldehyde | HCID 541 | — |
| Reactant | 8-Hydroxyquinoline | HCID 1923 | — |
| Reactant | Benzocaine | HCID 2337 | — |
| Product | HCID 67126855 | HCID 67126855 | — |
Reaction Steps
The title compound was prepared by both Method A and method B presented for the compound of Example 1 with the change that benzocaine (Sigma), 4-nitro-benzaldehyde (Sigma) and 8-hydroxy quinoline were used as starting materials. Product purified by column chromatography: C25H21N3O5; (MW: 443.2); yield; 50 mg (30.9%, Method A). HPLC (CH3CN/H2O 70:30 Phenomenex C-18 254 nm): Tr=8.82 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871937B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-285d06230fba4f7c871a7347c9508393 |
| Source note | uspto-grants-2014_10 |