HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Hydroxyquinoline → HCID 54673781, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Hydroxyquinoline | HCID 1923 | — |
| Reactant | 2-Amino-6-methylpyridine | HCID 15765 | — |
| Reactant | 3,4-Difluorobenzaldehyde | HCID 588088 | — |
| Product | HCID 54673781 | HCID 54673781 | — |
Reaction Steps
The title compound was prepared by method B presented for the compound of Example 1 with the change that 3,4-difluorobenzaldehyde was reacted with 2-amino-6-picoline and 8-hydroxy-quinoline. White powder precipitated, C22H17F2N3O, (MW: 377.1); yield; 275 mg (53.3%). m.p.: 162-165° C.; HPLC (CH3CN/H2O 70:30 Phenomenex C18 282 nm): 7.97 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871937B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-374aab20d5a4453faf44dbb6f29fed12 |
| Source note | uspto-grants-2014_10 |