HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → 2-(Azidomethyl)-1,3-difluorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 2-(Bromomethyl)-1,3-difluorobenzene | HCID 581435 | — |
| Catalyst | Tetrabutylammonium Bromide | HCID 74236 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | 2-(Azidomethyl)-1,3-difluorobenzene | HCID 10888323 | — |
Reaction Steps
A mixture of 2,6-diflourobenzyl bromide (100 gms), tetrabutylammonium bromide (10 gms), t-butanol (200 ml) and sodium azide (62.8 gm) were stirred at room temperature for 22-24 hours. After the completion, reaction mass was filtered and washed with t-butanol (2.5 ml ) to give 2-(azidomethyl)-1,3-difluorobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871945B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-45461d39fa254ee6865d531756c5b65a |
| Source note | uspto-grants-2014_10 |