(2R)-oxolane-2-carbohydrazide → HCID 178424709, compound

Participants

Role	Name	HCID	Charge
Reactant	(2R)-oxolane-2-carbohydrazide	HCID 40566306	—
Reactant	2-(Tetrahydrofuran-3-yl)acetohydrazide	HCID 68288816	—
Reactant	4-(1-(2,4-dimethyl-5-(5-((tetrahydrofuran-3-yl)methyl)-4H-1,2,4-triazol-3-yl)benzoyl)piperidin-4-yl)benzonitrile	HCID 178424704	—
Product	HCID 178424709	HCID 178424709	—

Reaction Steps

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of 4-(1-(2,4-dimethyl-5-(5-((tetrahydrofuran-3-yl)methyl)-4H-1,2,4-triazol-3-yl)benzoyl)piperidin-4-yl)benzonitrile (compound 130), using (R)-tetrahydrofuran-2-carbohydrazide (compound 133.1) instead of 2-(tetrahydrofuran-3-yl)acetohydrazide (compound 130.4). m/z (ES+) 446 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08871790B2
Source dataset	uspto-grants-2014_10
ORD ID	ord-70e708ad7cf2475cbdad68b9aae1de13
Source note	uspto-grants-2014_10