HCID 178419650, compound → 4-Cyclopentyl-2-methyl-5-(5-methyl-4H-1,2,4-triazol-3-yl)benzoic acid

HRID 541290Notes

Reaction equation

HRID 541290 reaction equation
[CH:1]1([C:5]2[C:13]([C:14]3[NH:18][C:17]([CH3:19])=[N:16][N:15]=3)=[CH:12][C:8]([C:9]([OH:11])=[O:10])=[C:7]([CH3:20])[CH:6]=2)[CH2:4][CH2:3][CH2:2]1.Br[Mg][CH:23]1CCCC1>>[CH:1]1([C:5]2[C:13]([C:14]3[NH:18][C:17]([CH3:19])=[N:16][N:15]=3)=[CH:12][C:8]([C:9]([OH:11])=[O:10])=[C:7]([CH3:20])[CH:6]=2)[CH2:2][CH2:3][CH2:23][CH2:4]1

Participants

3

Reactant 2

HCID 178419650HCID 178419650, compoundHCID 178433965HCID 178433965, compound

Product 1

HCID 1784339664-Cyclopentyl-2-methyl-5-(5-methyl-4H-1,2,4-triazol-3-yl)benzoic acid

Procedure

The title compound was synthesized using standard chemical manipulations and procedures similar to those used for the preparation of compound 152.8 and using bromo(cyclopentyl)magnesium in place of bromo(cyclobutyl)magnesium.

Sources & evidence

ORD record
ord-290c5860cb7c4d7bba1bc294b8011d4f
Source dataset
uspto-grants-2014_10
Patent number
US08871790B2

Reaction notes

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