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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 541486Generated: November 2, 2026

4-Chloro-5-iodo-2-methylbenzoic acid → 4-Chloro-5-formyl-2-methylbenzoic acid

https://huagongshe.com/reaction/541486

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-5-iodo-2-methylbenzoic acidHCID 68288948—
Reactant4-Cyclobutyl-5-formyl-2-methylbenzoic acidHCID 86672546—
Reactant4-(1-(4-Cyclobutyl-5-formyl-2-methylbenzoyl)piperidin-4-yl)benzonitrileHCID 86672547—
Product4-Chloro-5-formyl-2-methylbenzoic acidHCID 86672549—

Reaction Steps

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 392.2, except 4-chloro-5-iodo-2-methylbenzoic acid (compound 471.1) was used in place of 4-cyclobutyl-5-iodo-2-methylbenzoic acid (compound 392.1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08871790B2
Source datasetuspto-grants-2014_10
ORD IDord-b2a401a5e5244c3f9aaed7fb4875d884
Source noteuspto-grants-2014_10