Potassium Carbonate → HCID 57962250, compound

Participants

Reaction Steps

To a solution of 3,3′-propane-1,3-diyldianiline (41.0 mg, 0.181 mmol) in N,N-dimethylformamide (1.0 mL), potassium carbonate (72 mg, 0.52 mmol) was added followed by 2,4,5-trichloropyrimidine (20 μL, 0.17 mmol). The mixture was stirred for 2.5 hours and purified by preparative LCMS (pH 10) to give the desired product (21 mg, 32%). LCMS for C19H19Cl2N4 (M+H)+: m/z=373.1.

Provenance & Evidence