HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57962754, compound → HCID 57962576, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57962754 | HCID 57962754 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 57962576 | HCID 57962576 | 102.1% |
Reaction Steps
tert-Butyl {5-[(3-aminophenyl)ethynyl]-2-methyl-4-morpholin-4-ylphenyl}carbamate (62 mg, 0.15 mmol) was stirred in methanol (2 mL) and 10% palladium on carbon (50 mg). The mixture was stirred under a balloon pressure of hydrogen gas for 3 hours. The mixture was filtered through celite and evaporated to give the desired compound (63 mg, 100%). LCMS for C24H34N3O3 (M+H)+: m/z=412.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871753B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-34731872bfd141368bfdcf545ba47243 |
| Source note | uspto-grants-2014_10 |