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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 541567Generated: November 1, 2026

HCID 57962754, compound → HCID 57962576, compound

https://huagongshe.com/reaction/541567

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57962754HCID 57962754—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 57962576HCID 57962576102.1%

Reaction Steps

tert-Butyl {5-[(3-aminophenyl)ethynyl]-2-methyl-4-morpholin-4-ylphenyl}carbamate (62 mg, 0.15 mmol) was stirred in methanol (2 mL) and 10% palladium on carbon (50 mg). The mixture was stirred under a balloon pressure of hydrogen gas for 3 hours. The mixture was filtered through celite and evaporated to give the desired compound (63 mg, 100%). LCMS for C24H34N3O3 (M+H)+: m/z=412.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08871753B2
Source datasetuspto-grants-2014_10
ORD IDord-34731872bfd141368bfdcf545ba47243
Source noteuspto-grants-2014_10