HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-5-isocyanatopyridine → HCID 86636136, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-5-isocyanatopyridine | HCID 4961273 | — |
| Reactant | N-[6-Chloro-2,4,8,22-tetraazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20), 3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]piperidine-4-carboxamide bis(trifluoroacetate) | HCID 86636132 | — |
| Product | HCID 86636136 | HCID 86636136 | 23% |
Reaction Steps
The desired compound was prepared according to the procedure of Example A9, step H using N-[6-chloro-2,4,8,22-tetraazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20), 3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]piperidine-4-carboxamide bis(trifluoroacetate) and 2-chloro-5-isocyanatopyridine as starting materials in 23% yield. LCMS for C30H29Cl2N8O2 (M+H)+: m/z=603.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871753B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-8b693879db184aaa93c2e081426beacf |
| Source note | uspto-grants-2014_10 |