5-Methylisoxazole-3-carbonyl chloride → HCID 86636172, compound

Participants

Reaction Steps

The desired compound was prepared according to the procedure of Example A20, using tert-butyl-4-(2-[{6-chloro-2,4,8,22-tetraazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]amino}-2-oxoethyl)piperazine-1-carboxylate bis(trifluoroacetate) and 5-methylisoxazole-3-carbonyl chloride as starting materials in 56% yield. LCMS for C29H30ClN8O3 (M+H)+: m/z=573.2.

Provenance & Evidence