HuagongsheHuagongshe Chemistry Print Report · For research reference only
o-Toluenesulfonyl chloride → HCID 86636242, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | o-Toluenesulfonyl chloride | HCID 8623 | — |
| Reactant | N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-piperidin-4-ylacetamide tris(trifluoroacetate) | HCID 86636131 | — |
| Product | HCID 86636242 | HCID 86636242 | 18% |
Reaction Steps
The desired compound was prepared according to the procedure of Example A42 using N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-piperidin-4-ylacetamide tris(trifluoroacetate) and 2-methylbenzenesulfonyl chloride as starting materials in 18% yield. LCMS for C31H33ClN7O3S (M+H)+: m/z=618.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871753B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-47e30b8f9fe34638bf0bb6b845e81361 |
| Source note | uspto-grants-2014_10 |