HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyanobenzene-1-sulfonyl chloride → HCID 86636245, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyanobenzene-1-sulfonyl chloride | HCID 2801360 | — |
| Reactant | N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-piperidin-4-ylacetamide tris(trifluoroacetate) | HCID 86636131 | — |
| Product | HCID 86636245 | HCID 86636245 | 25% |
Reaction Steps
The desired compound was prepared according to the procedure of Example A42 using N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-piperidin-4-ylacetamide tris(trifluoroacetate) and 3-cyanobenzenesulfonyl chloride as starting materials in 25% yield. LCMS for C31H30ClN8O3S (M+H)+: m/z=629.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871753B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-2acdf59a39ec4bccbf20f24a8c322b1c |
| Source note | uspto-grants-2014_10 |