HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dimethylimidazole-4-sulfonyl chloride → HCID 86636247, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dimethylimidazole-4-sulfonyl chloride | HCID 2736256 | — |
| Reactant | N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-piperidin-4-ylacetamide tris(trifluoroacetate) | HCID 86636131 | — |
| Product | HCID 86636247 | HCID 86636247 | 24% |
Reaction Steps
The desired compound was prepared according to the procedure of Example A42 using N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-piperidin-4-ylacetamide tris(trifluoroacetate) and 1,2-dimethyl-1H-imidazole-4-sulfonyl chloride as starting materials in 24% yield. LCMS for C29H33ClN9O3S (M+H)+: m/z=622.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871753B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-73c5796c841e4250935ed9673f03e02f |
| Source note | uspto-grants-2014_10 |