Benzenamine, 3-ethynyl- → HCID 57962511, compound

HRID 541744Notes

Reaction equation

HRID 541744 reaction equation
Br[C:2]1[CH:3]=[C:4]([S:11]([NH:14][C:15]([CH3:18])([CH3:17])[CH3:16])(=[O:13])=[O:12])[CH:5]=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=1.[C:19]([C:21]1[CH:22]=[C:23]([CH:25]=[CH:26][CH:27]=1)[NH2:24])#[CH:20]>>[NH2:24][C:23]1[CH:22]=[C:21]([C:19]#[C:20][C:2]2[CH:3]=[C:4]([S:11]([NH:14][C:15]([CH3:18])([CH3:17])[CH3:16])(=[O:13])=[O:12])[CH:5]=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=2)[CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 104682Benzenamine, 3-ethynyl-HCID 57962279HCID 57962279, compound

Product 1

HCID 57962511HCID 57962511, compoundYield 32%

Procedure

The desired compound was prepared according to the procedure of Example B5, step E using 3-bromo-N-(tert-butyl)-5-nitrobenzenesulfonamide and 3-ethynylaniline as the starting materials in 32% yield. LCMS for C18H20N3O4S (M+H)+: m/z=374.2.

Sources & evidence

ORD record
ord-2866b66a6694452dbb2265cc9a624c0c
Source dataset
uspto-grants-2014_10
Patent number
US08871753B2

Reaction notes

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