Hydrochloric Acid → N-(3-Aminophenyl)-2-(3-nitrophenyl)acetamide Hydrochloride

Participants

Reaction Steps

Into the reaction was added tert-butyl (3-{[(3-nitrophenyl)acetyl]amino}phenyl)carbamate (0.46 g, 1.2 mmol) and 4.0 M of hydrogen chloride in 1,4-dioxane (3 mL). The mixture was stirred at rt for 2 h. The solvent was removed under vacuum to give the desired product (0.34 g, 100%) as a white powder. LCMS for C14H13N3O3 (M+H)+: m/z=272.0.

Provenance & Evidence