HCID 57962721, compound → HCID 57961604, compound

Participants

Reaction Steps

To a mixture of tert-butyl {6-[(3-aminophenyl)ethynyl]pyridin-2-yl}carbamate (70.0 mg, 2.3 mmol) in methanol (25 mL) and was added 10% palladium on carbon (700 mg, 0.60 mmol). The resultant mixture was hydrogenated at 60 psi for 3 hours. The reaction mixture was filtered, washed with MeOH and concentrated to give the desired product (680 mg, 96%). LCMS for C18H24N3O2 (M+H)+: m/z=314.1.

Provenance & Evidence