Butyryl chloride → HCID 57961570, compound

HRID 541882Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[NH:6][C:7]3[CH:8]=[CH:9][CH:10]=[C:11]([CH:23]=3)[CH2:12][NH:13][C:14]3[CH:22]=[C:18]([NH:19][C:20]=1[N:21]=2)[CH:17]=[CH:16][CH:15]=3.[C:24](Cl)(=[O:28])[CH2:25][CH2:26][CH3:27]>>[C:24]([N:13]1[CH2:12][C:11]2[CH:23]=[C:7]([CH:8]=[CH:9][CH:10]=2)[NH:6][C:5]2=[N:21][C:20](=[C:2]([Cl:1])[CH:3]=[N:4]2)[NH:19][C:18]2=[CH:22][C:14]1=[CH:15][CH:16]=[CH:17]2)(=[O:28])[CH2:25][CH2:26][CH3:27]

Participants

Reactant 2

HCID 8855Butyryl chloride

HCID 57961661HCID 57961661, compound

Product 1

HCID 57961570HCID 57961570, compoundYield 50%

Procedure

The desired compound was prepared as a white powder according to the procedure of Example C22, step F, using 6-chloro-2,4,8,14,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaene and butyryl chloride as the starting materials in 50% yield. LCMS for C21H21ClN5O (M+H)+: m/z=394.1.

Sources & evidence

ORD record: ord-bb5ce17c988344afb3fcdea73c51b526
Source dataset: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08871753B2

Reaction notes

Loading…