huagongshe.com
HRID541922

反应详情

EQUATION

反应方程式

HRID 541922 的结构方程式

REACTANTS

反应物

2
反应SMILES：Nc1cccc(CCO)c1
HCID14938987

2-(3-Aminophenyl)ethan-1-ol

C8H11NO

反应SMILES：CN(c1cccc(OC2CCCCO2)c1)c1nc(Cl)ncc1Cl
HCID57962415

未命名化合物

PRODUCTS

产物

1
反应SMILES：CN(c1cccc(O)c1)c1nc(Nc2cccc(CCO)c2)ncc1Cl
HCID57962584

未命名化合物

收率 59%

PROCEDURE

实验过程

The desired compound was prepared according to the procedure of Example D5, step B, using 2,5-dichloro-N-methyl-N-[3-(tetrahydro-2H-pyran-2-yloxy)phenyl]pyrimidin-4-amine and 2-(3-aminophenyl)ethanol [Bioorg. Med. Chem. 2005, 13, 6703-6712] as the starting materials in 59% yield. LCMS for C19H20ClN4O2 (M+H)+: m/z=371.1.