Pyridine → HCID 57961650, compound

Participants

Reaction Conditions

Reaction Steps

A solution of tert-butyl (3-{[(3-nitrobenzyl)amino]methyl}phenyl)carbamate trifluoroacetate (0.16 g, 0.34 mmol) in acetonitrile (5.2 mL) was treated with 4-dimethylaminopyridine (8.3 mg, 68 μmol), pyridine (0.14 mL, 1.7 mmol), and acetic anhydride (35 μL, 0.37 mmol) and stirred at 20° C. for 16 h. The reaction mixture was purified by preparative LCMS to give the desired product (95 mg, 70%). LCMS for C21H25N3O5Na (M+Na)+: m/z=422.0.

Provenance & Evidence