HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Methyl-1H-pyrazole-3-carbonyl chloride → HCID 86636321, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Methyl-1H-pyrazole-3-carbonyl chloride | HCID 12845045 | — |
| Edukt | N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-[(3S)-pyrrolidin-3-yl]acetamide tris(trifluoroacetate) | HCID 86636313 | — |
| Produkt | HCID 86636321 | HCID 86636321 | 82% |
Reaktionsschritte
The desired compound was prepared according to the procedure of Example D94 using N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-[(3S)-pyrrolidin-3-yl]acetamide tris(trifluoroacetate) and 1-methyl-1H-pyrazole-3-carbonyl chloride as the starting materials in 82% yield. LCMS for C28H29ClN9O2 (M+H)+: m/z=558.1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08871753B2 |
| Quelldatensatz | uspto-grants-2014_10 |
| ORD ID | ord-7e56fc91f7fe413a8a50ba5178a92059 |
| Quellennotiz | uspto-grants-2014_10 |