HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-1,2-oxazole-4-carbonyl chloride → HCID 86636323, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-1,2-oxazole-4-carbonyl chloride | HCID 2759917 | — |
| Reactant | N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-[(3S)-pyrrolidin-3-yl]acetamide tris(trifluoroacetate) | HCID 86636313 | — |
| Product | HCID 86636323 | HCID 86636323 | 91% |
Reaction Steps
The desired compound was prepared according to the procedure of Example D94 using N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-[(3S)-pyrrolidin-3-yl]acetamide tris(trifluoroacetate) and 5-methylisoxazole-4-carbonyl chloride as the starting materials in 91% yield. LCMS for C28H28ClN8O3 (M+H)+: m/z=559.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871753B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-f4377b5de96c4ab19b5bddb3bbdf4aad |
| Source note | uspto-grants-2014_10 |