HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-azetidin-3-yl-N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]acetamide tris(trifluoroacetate) → HCID 178520342, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-azetidin-3-yl-N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]acetamide tris(trifluoroacetate) | HCID 86636333 | — |
| Reactant | HCID 178524907 | HCID 178524907 | — |
| Product | HCID 178520342 | HCID 178520342 | 57% |
Reaction Steps
The desired compound was prepared according to the procedure of Example D97, step A, using 2-azetidin-3-yl-N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]acetamide tris(trifluoroacetate) and 1H-1,2,4-triazole-3-carboxylic acid as the starting materials in 57% yield. LCMS for C25H24ClN10O2 (M+H)+: m/z=531.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871753B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-e3c25650a7bf47be805779d015d3d415 |
| Source note | uspto-grants-2014_10 |