HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1,3,4-thiadiazole → HCID 86636341, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1,3,4-thiadiazole | HCID 2795198 | — |
| Reactant | 2-azetidin-3-yl-N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]acetamide tris(trifluoroacetate) | HCID 86636333 | — |
| Product | HCID 86636341 | HCID 86636341 | 20% |
Reaction Steps
The desired compound was prepared according to the procedure of Example A157 using 2-azetidin-3-yl-N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]acetamide tris(trifluoroacetate) and 2-bromo-1,3,4-thiadiazole as the starting materials in 20% yield. LCMS for C24H23ClN9OS (M+H)+: m/z=520.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871753B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-877e76f8b6b64f029f4819f1b7f79657 |
| Source note | uspto-grants-2014_10 |