tert-Butyl isocyanate → HCID 86636405, compound

Participants

Reaction Steps

The desired compound was prepared according to the procedures of Example D41, using 6-chloro-12-(2-oxo-2-piperazin-1-ylethoxy)-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaene tris(trifluoroacetate) and 2-isocyanato-2-methylpropane as the starting materials, and Example D87 in 60% yield (2 steps). LCMS for C24H26ClN8O3 (M+H)+: m/z=509.0.

Provenance & Evidence