Acetic Anhydride → HCID 13769579, compound

HRID 542099Notes

Reaction equation

HRID 542099 reaction equation
[OH:1][CH2:2][C:3]1[CH:8]=[C:7]([CH3:9])[N:6]=[C:5]([NH:10][C:11]([NH:13][S:14]([C:17]2[CH:26]=[CH:25][CH:24]=[CH:23][C:18]=2[C:19]([O:21][CH3:22])=[O:20])(=[O:16])=[O:15])=[O:12])[N:4]=1.[C:27](OC(=O)C)(=[O:29])[CH3:28]>N1C=CC=CC=1>[C:27]([O:1][CH2:2][C:3]1[CH:8]=[C:7]([CH3:9])[N:6]=[C:5]([NH:10][C:11]([NH:13][S:14]([C:17]2[CH:26]=[CH:25][CH:24]=[CH:23][C:18]=2[C:19]([O:21][CH3:22])=[O:20])(=[O:16])=[O:15])=[O:12])[N:4]=1)(=[O:29])[CH3:28]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 13769578HCID 13769578, compound

Product 1

HCID 13769579HCID 13769579, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To 0.5 g of the compound from Example 5 was added 1 ml of acetic anhydride and 1 ml of pyridine. After 1 hour at room temperature, ice-water was added, the precipitated oil was triturated, filtered, and washed with water to afford 0.4 g of the title compound, m.p. 145°-150°.

Workup

  1. customthe precipitated oil was triturated
  2. filtrationfiltered
  3. washwashed with water

Sources & evidence

ORD record
ord-50869792f74d437193916d706ac2200f
Source dataset
uspto-grants-1987_04
Patent number
US04655823

Reaction notes

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