Isopropyl iodide → HCID 13882872, compound

Participants

Reaction Steps

A mixture of 15.0 g (0.047 mol) of product of Example 5, 6.5 g (0.047 mol) of K2CO3 and 5.2 ml (0.52 mol) of 2-iodopropane in 100 ml of acetone was stirred at reflux for 64 hours. The cooled reaction mixture was concentrated in vacuo. The residue was dissolved in ether, washed with H2O, dried (MgSO4), and concentrated in vacuo to a brown oil which was kugelrohr distilled at 68 Pa, pot temperature 90° C., affording 15.11 g (88.9%) of product as a clear oil, nD25 1.4405.

Provenance & Evidence