2,6-Lutidine → HCID 13882879, compound

Participants

Reaction Steps

This compound was prepared as described in Example 19: 75 g (0.235 mol) of product of Example 5, 50.29 g (55 ml, 0.469 mol) of 2,6-lutidine and 252.66 g (214 ml, 2.3 mol) of phosphorus oxychloride were reacted affording 68 g of a black oil. Crude was purified by kugelrohr distillation at 200 Pa, pot temperature 110° C., to give 48 g (60%) of product as a yellow oil; nD25 1.4466.

Provenance & Evidence