反应详情

To a solution of 2-mercaptobenzothiophene (1.8 g, 10.8 mmol) in toluene under nitrogen was added N-benzylpiperazine (1.88 ml, 10.8 mmol) and the mixture heated at reflux for 1.5 h. Left to cool, concentrated in vacuo and product recrystallised from diethyl etherhexane to yield the title compound (1.55 g), m.p. 160°-161° C.

1. temperaturethe mixture heated
2. temperatureat reflux for 1.5 h
3. waitLeft
4. temperatureto cool
5. concentrationconcentrated in vacuo and product
6. customrecrystallised from diethyl etherhexane