反应详情

温度

50 °C

n-Octyloxybenzene (301 g, 1.46 mol), succinic anhydride (146.8 g, 1.468 mol) and carbon disulfide (1.3 l) were agitated at room temperature, followed by portion-wise feeding anhydrous aluminum chloride (392 g, 2.94 mol), further agitating the mixture at 50° C. for 4 hours after the reaction became quiet, cooling the mixture down to room temperature, adding it to ice (2 Kg), distilling off carbon disulfide, collecting solids, adding toluene (1 l), distilling off water on heating, filtering while hot, and distilling off toluene under reduced pressure to obtain oily β-(p-octyloxybenzoyl)-propionic acid (238 g, yield 53%).

1. temperaturecooling the mixture down to room temperature
2. distillationdistilling off carbon disulfide
3. customcollecting solids
4. additionadding toluene (1 l)
5. distillationdistilling off water
6. temperatureon heating
7. filtrationfiltering while hot, and
8. distillationdistilling off toluene under reduced pressure