HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine ethyl ester, hydrochloride → Benzhydrol, alpha-(aminomethyl)-, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine ethyl ester, hydrochloride | HCID 2723640 | — |
| Reactant | HCID 178478979 | HCID 178478979 | — |
| Product | Benzhydrol, alpha-(aminomethyl)-, hydrochloride | HCID 201827 | — |
Reaction Steps
Treatment of ethyl glycinate hydrochloride (4.5 g) with phenylmagnesium chloride (from 0.39 mole each of bromobenzene and magnesium), as discussed by A. McKenzie and G. O. Wills J. Chem. Soc. 1925, 127, 283 (and references cited therein), affords the title compound (mp 191°-193° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04657897 |
| Source dataset | uspto-grants-1987_04 |
| ORD ID | ord-6a15725e527245438007c42667c59ea2 |
| Source note | uspto-grants-1987_04 |