反应详情

温度

80 °C

A mixture of 33.3 g of 3-(N-methyl N-benzylamino)quinuclidine and 16 g of palladium on charcoal at 10% (50% humidity) in 500 ml of ethanol is heated in an autoclave at 80° C. for 6 hours 30 minutes and under a hydrogen pressure of 6 bars. Then it is filtered, the solvent is evaporated (under a good vacuum and when cold) and the residue is distilled (Boiling point [24 mm/Hg]=110° C.). Thus the expected product is obtained with a yield of 43%.

1. filtrationThen it is filtered
2. customthe solvent is evaporated (under a good vacuum and when cold) and the residue
3. distillationis distilled (Boiling point [24 mm/Hg]=110° C.)