HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 5-(4-Aminophenyl)-3-methyl-2(1H)-pyrazinone hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 5-(4-benzyloxycarbonylaminophenyl)-3-methyl-2(1H)-pyrazinone | HCID 13853561 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-(4-Aminophenyl)-3-methyl-2(1H)-pyrazinone hydrobromide | HCID 20208651 | — |
Reaction Steps
5-(4-Benzyloxycarbonylaminophenyl)-3-methyl-2(1H)pyrazinone (1.5 g) was treated with hydrogen bromide in acetic acid in a manner similar to that described in Example 20 to give the title compound as its hydrobromide salt (1.09 g) which on recrystallisation from ethanol/ether has m.p. >300° C.; ν(Nujol mull) 1632, 1640 cm-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04657906 |
| Source dataset | uspto-grants-1987_04 |
| ORD ID | ord-243e3a70be064ea88fee6a8ffaa8246e |
| Source note | uspto-grants-1987_04 |