HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrobenzoyl chloride → 4-Nitro-N-[4-(5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrobenzoyl chloride | HCID 8502 | — |
| Reactant | 5-(4-Aminophenyl)pyrazin-2(1H)-one | HCID 12358028 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 4-Nitro-N-[4-(5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide | HCID 13853566 | 49.1% |
Reaction Steps
A solution of 5-(4-aminophenyl)-2(1H)-pyrazinone (1.7 g) in sodium hydroxide was reacted with 4-nitrobenzoyl chloride (1.8 g) in a manner similar to that described in Example 9 to give 5-[4-(4-nitrobenzamido)phenyl]-2(1H)-pyrazinone (1.5 g, m.p. 298°-300° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04657906 |
| Source dataset | uspto-grants-1987_04 |
| ORD ID | ord-f9b05aa3866944c4a6767205aac1407e |
| Source note | uspto-grants-1987_04 |