Sulfuric Acid → HCID 20208470, compound

HRID 542500Notes

Reaction equation

HRID 542500 reaction equation
C(O)(=O)C.[CH2:5]([NH:9][C:10]1[O:15][C:14](=[O:16])[C:13]2[C:17]([CH2:21][CH3:22])=[CH:18][CH:19]=[CH:20][C:12]=2[N:11]=1)[CH2:6][CH2:7][CH3:8].[S:23](=[O:27])(=[O:26])([OH:25])[OH:24]>O>[S:23]([OH:27])([OH:26])(=[O:25])=[O:24].[CH2:5]([NH:9][C:10]1[O:15][C:14](=[O:16])[C:13]2[C:17]([CH2:21][CH3:22])=[CH:18][CH:19]=[CH:20][C:12]=2[N:11]=1)[CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 20208557HCID 20208557, compound

Product 1

HCID 20208470HCID 20208470, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2-n-butylamino-5-ethyl-4H-3,1-benzoxazin-4-one acetate (1.0 g) is dissolved in 50 ml water containing a stoichiometric equivalent of sulfuric acid, and the solution evaporated to dryness. The product is suspended in ether and filtered, air dried and recrystallized from methanol/acetone to yield 2-n-butylamino-5-ethyl-4H-3,1-benzoxazin-4-one sulfate.

Workup

  1. customthe solution evaporated to dryness
  2. filtrationfiltered
  3. customair dried
  4. customrecrystallized from methanol/acetone

Sources & evidence

ORD record
ord-8cfe375007994721a2a072fdf1710820
Source dataset
uspto-grants-1987_04
Patent number
US04657893

Reaction notes

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