Water → HCID 13672383, compound

Participants

Reaction Steps

In this example, 5 m moles of 4-benzyloxy-2-(10-formyldecyl) quinoline-N-oxide is dissolved in acetone, and 10 m moles of Jones' reagent prepared from chromium trioxide, sulfuric acid and water is added thereto with ice cooling. The mixture is stirred for 5 minutes. After the reaction, water is added thereto, and the reaction mixture is extracted with chloroform. The extract is dried over anhydrous sodium sulfate, and then the solvent is removed therefrom by distillation. The residue is purified by silica gel column procedure, whereby the captioned compound is obtained as colorless crystals (yield: 31.0%).

Provenance & Evidence