Ammonium Acetate → HCID 13672384, compound

Participants

Reaction Steps

In this example, 5 m moles of 4-benzyloxy-2-(10-formyldecyl) quinoline-N-oxide is dissolved in methanol, and 50 m moles of ammonium acetate and 15 m moles of sodium cyanoborohydride are added thereto with ice cooling. Then, the mixture is stirred for 1.5 hours. After the reaction, the solvent is removed therefrom by distillation, and then the mixture is extracted with chloroform. The chloroform layer is dried over anhydrous sodium sulfate, and the solvent is removed therefrom by distillation. The residue is purified by silica gel column procedure, whereby the captioned compound is obtained as colorless crystals (yield: 21.5%).

Provenance & Evidence