Hydroxyamine hydrochloride → HCID 13732600, compound

Participants

Reaction Steps

1-Ethyl-5-(3-fluorobenzoyl)-4-hydroxy-1H-pyrazolo[3,4-b]pyridine (2.85 g) was refluxed overnight in 50 ml of pyridine containing 3.0 g of hydroxylamine hydrochloride. The pyridine was evaporated and the residue triturated with 5% hydrochloric acid. The product thus obtained was filtered off and recrystallized from methanol to give 2.21 g of analytically pure product, mp 136°-137° C.

Provenance & Evidence