Methane → HCID 13853487, compound

Participants

Reaction Steps

A mixture of 2,4 g (97.3 mmol) of 2-carbomethoxy-6-chloro-N,N-diacetyl-3,4-dimethoxyaniline and 20 mL of 2N sodium hydroxide was refluxed 3.5 hours. The solution was treated with Darco and neutralized with 5 mL of glacial acetic acid. Upon cooling, the product crystallized and was collected by filtration to yield 0.6 g (36%) of a fluffy yellow solid, mp 140°-142° C. NMR (CDCl3) δ 3.82 (s, 3H, OCH3), 4.03 (s, 3H, OCH3). 7.15 (s, 1H, ArH).

Provenance & Evidence