Iodoethane → HCID 13474421, compound

Participants

Reaction Steps

A mixture of 4-hydroxy-3-(1-methyl-1H-tetrazol-5-yl)quinoline (2 g), ethyl iodide (1.1 ml), anhydrous potassium carbonate (1.83 g) and dimethylformamide (100 ml) was stirred and heated on a steam bath for 18 hours. The mixture was evaporated under reduced pressure and the residue dissolved in industrial methylated spirit (100 ml). Dilution with diethyl ether (100 ml) gave a white precipitate which was collected and extracted with hot dichloromethane (100 ml). The extract was evaporated to give the novel compound 1-ethyl-3-(1-methyl-1H-tetrazol-5-yl)-4-quinolone, m.p. 170°-176°.

Provenance & Evidence