HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Sulfide → 1-Ethyl-1H-pyrrole-2-carbothioamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Sulfide | HCID 402 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Ethyl-1H-pyrrole-2-carbonitrile | HCID 13589307 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 1-Ethyl-1H-pyrrole-2-carbothioamide | HCID 3063497 | 65% |
Reaction Steps
The 1-ethylpyrrole-2-carbonitrile obtained above (3.0 g, 25 mmole) is dissolved in a solution of triethylamine (12.5 g, 125 mmole) in pyridine (13 ml), and therein hydrogen sulfide is blown at 20° C. for 6 hours. To the reaction mixture is added water (300 ml). The precipitated crystals are separated by filtration, dried, and then recrystallized from ligroin to give 1-ethylpyrrole-2-carbothioamide (2.5 g, yield: 65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04659726 |
| Source dataset | uspto-grants-1987_04 |
| ORD ID | ord-1be1101b6bdf464daaf6ee2ce0c0a92a |
| Source note | uspto-grants-1987_04 |