HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-bromopyridine → HCID 70427236, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-bromopyridine | HCID 70622 | — |
| Reactant | 3-Ethoxy-2-(4-methylbenzene-1-sulfonyl)-1-phenylprop-2-en-1-one | HCID 54362331 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 70427236 | HCID 70427236 | 34% |
Reaction Steps
A solution of 1-benzoyl-2-ethoxy-1-(4-methylphenylsulphonyl)ethene (0.85 g) and 2-amino-5-bromopyridine (0.45 g) in dimethylacetamide (30 ml) was heated at reflux for 2 hours. It was then cooled and poured onto ice (60 g). The resulting off-white precipitate was filtered off, washed with water, dried, and recrystallised from ethyl acetate, to give 1-benzoyl-2-(5-bromopyrid-2-ylamino)-1-(4-methylphenylsulphonyl)ethene (0.4 g), m.p. 205° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04659727 |
| Source dataset | uspto-grants-1987_04 |
| ORD ID | ord-37f187f3d4354b6fb6d7eed3028ca29e |
| Source note | uspto-grants-1987_04 |