Diethyl (ethoxymethylene)malonate → HCID 2267686, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-amino-3-methylpyridine (5.5 g) and 2-ethoxy-1,1-bis(ethoxycarbonyl)ethene (10.8 g) was heated in a heating bath at 135° C. for 30 minutes. It was then cooled and triturated with light petroleum ether (b.p. 40°-60° C.). The resulting crude solid was recrystallised from light petroleum ether (b.p. 40°-60° C.), to give 1,1-bis(ethoxycarbonyl)-2-(3-methylpyrid-2-ylamino)ethene (10.3 g), m.p. 65°-67° C.

Provenance & Evidence