L-(-)-Sorbose → alpha-L-Sorbofuranose, 2,3:4,6-bis-o-(1-methylethylidene)-

Participants

Reaction Conditions

Reaction Steps

To 200 ml of acetone were added 10.0 g of L-sorbose and 65.0 mg of antimony pentafluoride, and the mixture was refluxed with stirring in a water bath of 60° C. for 6 hours. During this reaction, the refluxing solvent was dried with 20 g of Molecular Sieves 3A interposed between the reaction vessel and the condenser. The quantitative analysis of the reaction solution according to the same procedure as described in Example 14 showed that there was obtained 11.89 g (82.3%) of 2,3:4,6-di-O-isopropylidene-α-L-sorbofuranose.

Provenance & Evidence