HCID 86741434, compound → HCID 70423742, compound

Participants

Reaction Steps

5% Palladium-on-charcoal catalyst (0.025 g.) was added to a solution of N-n-butyl-8-(3,17β-dihydroxyoestra-1,3,5(10)-trien-7α-yl)oct-5-enamide (Example 3; 0.05 g.) in ethyl acetate (2.5 ml.) and the mixture was stirred at laboratory temperature under an atmosphere of hydrogen for 1 hour and then filtered. The filtrate was evaporated to dryness and there was thus obtained as oily residue N-n-butyl-8-(3,17β-dihydroxyoestra-1,3,5(10)-trien-7α-yl)octanamide, the structure of which was confirmed by spectroscopic means.

Provenance & Evidence