HCID 20206891, compound → HCID 70447180, compound

Participants

Reaction Steps

The process described in the last paragraph of Example 6 was repeated except that (8-hexanamidooctyl)triphenylphosphonium bromide was used in place of (9-carboxynonyl)triphenylphosphonium bromide. The hydrogenation process described in the second paragraph of Example 6 was then repeated using the N-[9-(3-benzyloxy-17β-hydroxyoestra-1,3,5(10)-trien-7α-yl)non-8-enyl]hexanamide thus obtained as starting material, and there was thus obtained as an oil N-[9-(3,17β-dihydroxyoestra-1,3,5(10)-trien-7α-yl)nonyl]hexanamide, the structure of which was confirmed by proton magnetic resonance and mass spectroscopy.

Provenance & Evidence